chronic Archives - Mediarabe

Researchers get to the roots of chronic stress and depression

October 13, 2020

A study in mice provides clues about the common molecular origins of chronic stress and depression. The discovery could inform new treatments for mood disorders.

Millions of years ago, our ancestors evolved the physiological responses needed to survive in the face of sudden threats from rivals and predators.

The release of hormones, including epinephrine (adrenaline), noradrenaline (norepinephrine), and the steroid hormone cortisol, trigger these “fight-or-flight” stress responses.

However, sustained or chronic stress that does not resolve when the immediate threat passes is a major risk factor for the development of mood disorders such as anxiety and depression.

Traumatic experiences, for example, in military combat, can also damage the body’s ability to regulate its stress responses, causing post-traumatic stress disorder.

People with these mood disorders have abnormally high and sustained stress hormone levels, which puts them at an increased risk of developing cardiovascular disease.

Researchers at the Karolinska Institutet in Stockholm,

Gossamer Bio Announces Topline Results for Phase 2 Trials of Oral GB001 in Asthma and Chronic Rhinosinusitis

October 13, 2020

| No Comments

| Health

– Primary endpoint of asthma worsening not met in LEDA Study, however consistent numeric reductions ranging from 32-35% observed across all three GB001 groups –

– Statistically significant improvements in key secondary endpoint of time to first asthma worsening of 28% and 30% observed for 20 mg and 60 mg doses of GB001, respectively; 23% improvement observed in 40 mg group –

– TITAN Study in chronic rhinosinusitis did not meet primary or secondary endpoints –

– Gossamer to hold webcast to discuss trial results at 8:00 am EDT –

Gossamer Bio, Inc. (Nasdaq: GOSS), a clinical-stage biopharmaceutical company focused on discovering, acquiring, developing and commercializing therapeutics in the disease areas of immunology, inflammation and oncology, today announced topline results from its Phase 2b LEDA trial in patients with moderate-to-severe eosinophilic asthma and its Phase 2 TITAN trial in patients with chronic rhinosinusitis.

“While we did not achieve statistical significance

Regenerative Medicine Market | Increasing Prevalence of Chronic Diseases to Boost the Market Growth

October 9, 2020

| No Comments

| Health Article

The global regenerative medicine market size is poised to grow by USD 9.55 billion during 2020-2024, progressing at a CAGR of over 20% throughout the forecast period, according to the latest report by Technavio. The report offers an up-to-date analysis regarding the current market scenario, latest trends and drivers, and the overall market environment. The report also provides the market impact and new opportunities created due to the COVID-19 pandemic. Download a Free Sample of REPORT with COVID-19 Crisis and Recovery Analysis.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20201009005293/en/

Technavio has announced its latest market research report titled Global Regenerative Medicine Market 2020-2024 (Graphic: Business Wire)

The increasing prevalence of various chronic diseases is one of the primary factors which will drive regenerative medicine market growth during the forecast period. The incidence of many musculoskeletal disorders and bone injuries such as arthritis, osteoporosis, and severe limb

Chronic health problems found in recovered COVID-19 patients – report

October 7, 2020

| No Comments

| Health Center

A new report by Israel’s Coronavirus Knowledge and Information Center released on Tuesday reveals how pervasive the so-called “COVID Long” phenomenon has become, and said that according to research, many of those who have recovered from the coronavirus face long-term complications. The report looked at medical research from all over the world and gave some recommendations for Israel’s medical establishment on how to cope with persistent medical problems of those who have recovered from the virus.

Symptoms of COVID Long can affect even those who had mild cases and who were young and in good health when they first became ill, the report said. These persistent symptoms can have a widespread effect on the patients’ nervous, cardiovascular and respiratory systems, as well as their mental health.

The researchers found that the COVID Long phenomenon was similar to lasting complications of other coronaviruses such as SARS and MERS. Some of those

Expert looks at how COVID-19 problems can turn into lifelong chronic diseases

October 1, 2020

| No Comments

| Health News

Once a patient is finished fighting COVID-19, their battle might not be over, as some effects could linger and even be worse than the virus itself.

Long-haulers are starting to realize the long-term effects are no joke. The effects could stay with a person for months, years or possibly the rest of a person’s life.

A long-hauler and an expert who studies the new part of the coronavirus fight spoke with sister station KOCO about the lingering effects.

“It’s important to know COVID is not an all or nothing, you die or you’re fine. There’s a whole lot in the middle ground that could impact lives for a very long time,” said Eliza Chakravarty, with the Oklahoma Medical Research Foundation.

That’s what Brad Benefield, of Moore, Oklahoma, is now realizing.

“I feel like I have the energy to go do stuff and then, whenever I start, it’s like, ‘Oh no.

Where you live may raise your odds of developing this chronic health problem

September 30, 2020

| No Comments

| Health Food

The neighborhoods we live in dictate a whole lot about our lives. The stores we patronize or the schools our children attend, just to name a few examples.

Now, a new study from Drexel University concludes that one’s neighborhood may also put them at a considerably higher risk of developing chronic kidney disease.

In more exact terms, the research team says people living in low socioeconomic neighborhoods (low average income, low average education level) may be more susceptible to chronic kidney disease, high blood pressure, and poor blood sugar control.

Besides just your neighbor’s finances, a neighborhood’s walkability, availability of healthy food options, and rate of violent crime all appear to influence residents’ odds of developing chronic kidney disease as well.

“Our finding, that people who are living in neighborhoods with the fewest resources are at highest risk for kidney disease, should be a call to health providers to integrate

FDA approved opioids for chronic pain despite lacking ‘critical’ safety data, analysis finds

September 28, 2020

| No Comments

| Health News

Sept. 28 (UPI) — The U.S. Food and Drug Administration approved nearly 50 new prescription opioid pain medications between 1997 and 2018, even though it lacked “critical” data on safety and effectiveness, an analysis published Monday by the journal Annals of Internal Medicine found.

None of the 48 drugs granted agency approval during the more than 20-year period was evaluated in clinical trials that lasted longer than 12 weeks, and the trials often included narrowly defined groups of patients, researchers said.

And few included “systematic assessments” of risks associated with these medications, including addiction potential and non-medical use.

“Our analysis provides a window through which to view the FDA’s opioid regulation over the past 20 years,” study co-author Dr. Caleb Alexander, founding co-director of the Center for Drug Safety and Effectiveness at Johns Hopkins Bloomberg School of Public Health, told UPI.

“We found the FDA often approved new opioids based