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Tag: Cervical

Balstilimab, Zalifrelimab Active in Advanced Cervical Cancer

October 12, 2020
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| Health News

Checkpoint blockade with the PD-1 inhibitor balstilimab, alone or in combination with the anti-CTLA-4 drug zalifrelimab, showed activity in women with recurrent or metastatic cervical cancer, preliminary results from two phase II trials indicated.

In patients treated with balstilimab alone, the overall response rate (ORR) was 14%, including complete responses in 2%, reported David O’Malley, MD, of the Ohio State University Comprehensive Cancer Center in Columbus.

And in those who received both investigational agents — balstilimab plus zalifrelimab — the ORR increased to 22%, including complete responses in 6%.

“What is really interesting about the combination arm is that while we did see a median duration of response in the single-agent [arm] that was a very impressive 15 months, the duration of response has not been reached in the combination arm,” O’Malley told MedPage Today.

He said that the tripling of the complete response rate as well as the better

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Cervical Cancer Therapeutics Market | Rising Prevalence of Cervical Cancer to Boost the Market Growth

October 10, 2020
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| Health

The global cervical cancer therapeutics market size is poised to grow by USD 1.06 billion during 2020-2024, progressing at a CAGR of over 7% throughout the forecast period, according to the latest report by Technavio. The report offers an up-to-date analysis regarding the current market scenario, latest trends and drivers, and the overall market environment. The report also provides the market impact and new opportunities created due to the COVID-19 pandemic. Download a Free Sample of REPORT with COVID-19 Crisis and Recovery Analysis.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20201009005348/en/

Technavio has announced its latest market research report titled Global Cervical Cancer Therapeutics Market 2020-2024 (Graphic: Business Wire)

There has been an increase in the prevalence of several female health conditions such as breast cancer and gynecological cancer, including cervical cancer. As a result, various organizations across the globe are conducting health initiatives towards the prevention

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HPV Vaccine Shown to Substantially Reduce Cervical Cancer Risk

October 4, 2020
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| Health

Quadrivalent human papillomavirus (HPV) vaccination was associated with a substantial reduction in the incidence of cervical cancer in a Swedish review of more than 1 million girls and women vaccinated from 2006–2017.

It’s been shown that the vaccine (Gardasil) helps prevent genital warts and high-grade cervical lesions, but until now, data on the ability of the vaccine to prevent cervical cancer, although widely assumed, had been lacking.

“Our results extend [the] knowledge base by showing that quadrivalent HPV vaccination is also associated with a substantially reduced risk of invasive cervical cancer, which is the ultimate intent of HPV vaccination program,” said investigators led by Jiayao Lei, PhD, a researcher in the Department of Medical Epidemiology and Biostatistics at the Karolinska Institute, Stockholm, Sweden.

The study was published online October 1 in The New England Journal of Medicine.

“This work provides evidence of actual cancer prevention,” commented Diane Harper, MD,

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