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Concerns are being raised over an increased risk of severe COVID-19 outcomes in multiple sclerosis (MS) patients on anti-CD20 B-cell depleting drugs such as ocrelizumab and rituximab following presentation of new data.
A Global Data Sharing Initiative study, including information on more than 1500 MS patients, most of whom had suspected or confirmed COVID-19, has shown increased risks of hospital admission, treatment in the intensive care unit (ICU), and ventilation for patients on ocrelizumab and rituximab compared with other MS drugs.
The study was presented at a special session on multiple sclerosis and COVID-19 at a final “Encore” event on September 26 as part of the 8th Joint European Committee for Treatment and Research in Multiple Sclerosis-Americas Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS-ACTRIMS) 2020, this year known as MSVirtual2020.
This adds to an